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36). Subjective wettability grades after 5 mins, 8 hrs, and 12 hrs differed significantly for etafilcon A (P less then 0.01) and omafilcon A (p less then 0.01), but not for nelfilcon A (p = 0.05), DDCLs. Conclusion Grading was sufficiently sensitive to differentiate the wettability performances of the three lens materials. Nelfilcon A maintained wettability over the wearing period, whereas etafilcon A material showed faster dewetting at 8 and 12 hrs than at 5 mins after lens insertion. © 2020 Müller et al.We present the c