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To evaluate the clinical diagnostic efficacy of accelerated 3D magnetic resonance (MR) neuroimaging by radiological assessment for image quality and artefacts. Prospective healthy volunteer study. Eight healthy subjects. Inversion Recovery (IR) prepared 3D Gradient Echo (GRE) sequence on a 1.5T GE Signa HDx scanner. Independent radiological diagnostic quality assessments of accelerated 3D MR brain datasets were carried out by four experienced neuro-radiologists who were blinded to the acceleration factor and to the subject. The radiolo