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In this research, we evaluate epicardial adiposity in physiologic and pathologic states and the effect of incretin-based drugs.G protein-coupled receptors (GPCRs) represent a large superfamily of cell-surface proteins that mediate mobile signaling and regulate virtually numerous areas of physiological and pathological processes, therefore offering as an abundant source of medication goals. As intrinsically allosteric proteins, numerous functions of GPCRs are regulated via allostery, wherein al