https://www.selleckchem.com/mTOR.html
CypB silencing/knockout leads to Slug, but not Snail, down-regulation. CypB's support of Slug expression depends on its endoplasmic reticulum location, where it interacts with calreticulin, a calcium-buffering chaperone related to Slug expression. Since CypB silencing reduces ionomycin-induced calcium release and Slug up-regulation, we suggest that Slug expression may rely on CypB modulation of calreticulin-dependent calcium signaling. In conclusion, this work uncovers new roles for CypA and CypB in modulating TECs plasticity and identifies CypB as
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