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Challenges of ADHD in Women and Girls Untreated ADHD symptoms can lead to many issues for girls and women. They may feel incompetent at work, experience difficulties in social relationships or experience anxiety and depression. They also tend to be better in establishing coping mechanisms that mask their ADHD symptoms, which makes it more difficult to be diagnosed and treated. Signs and symptoms Although research shows that ADHD affects both men and boys at a higher rate than girls and women, the gender gap narrows as