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The appearance of numerous chemokines and adhesion particles by corneal fibroblasts determines the discerning recruitment and activation of inflammatory cells in a way dependent on the type of insult. In infectious keratitis, the interaction of corneal fibroblasts with various aspects of microbes and with cytokines derived from infiltrated inflammatory cells results in excessive degradation of stromal collagen and consequent corneal ulceration. Corneal fibroblasts distinguish bet