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Herein, we introduce the neural networks of the brain that glioma surgeons need to be aware of, and further describe the indications, methods, and usefulness of awake craniotomy for preserving these networks. In addition, we will discuss topics expected to become the standard in the near future.We previously proposed an information-guided surgery based on objective intraoperative information to achieve a high precision and maximum resection of gliomas. In 2000, an "intelligent operating room" was constructed and put into operation as a p