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Distinct functions of NO in diverse interactions of host plants with fungal and oomycete pathogens of different lifestyles are highlighted, where NO in interplay with reactive oxygen species governs successful plant colonization, cell death, and establishment of resistance. Leicester was the first city in the UK to have 'local lockdown' measures imposed in response to high community rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. As part of this response, a directive was issued by NHS England to offer