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Finding the Best ADHD Medication For Adults Many adult ADHD treatment programs are based around medication. Finding the right medication dosage and dosage isn't always straightforward. Stimulants: These drugs are used to treat hyperactivity and inattention. They work by increasing the levels of brain chemicals that transmit messages between nerve cells. They are usually taken multiple times per day and start working within less than an hour. Stimulants Most doctors start with stimulants to treat ADHD. They work by boosting activi