https://www.selleckchem.com/pr....oducts/pf-06826647.h
senescent cells, can improve cognitive ability in mice models. In this review, we ask questions about the role of senescent brain cells in brain plasticity and cognitive functions impairments and how senolytics can improve them. We will discuss whether neuronal plasticity, defined as morphological and functional changes at the level of neurons and dendritic spines, can be the hallmark of neuronal senescence susceptible to the effects of senolytics.Background The locus coeruleus (LC) is a nucleus in the human brainstem with a variety
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