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The genus Genista L. (family Fabaceae, subfamily Papilionoideae), with its cosmopolitan distribution, has attracted the human interest since ancient times, as it is used in folk medicine and mainly in the Mediterranean area for the treatment of respiratory diseases, rheumatic disorders, diabetes and ulcer, while it is also well known for its yellow pigment. The chemical composition of the Genista species revealed the presence of more than 108 flavonoids. Isoflavones, belonging to the group of phytoestrogens, are important secondary meta