https://www.selleckchem.com/products/sr59230a.html
Discrete calcium signals within the vascular endothelium decrease with age and contribute to impaired endothelial dependent vasodilation. Calreticulin (Calr), a multifunctional calcium binding protein and endoplasmic reticulum (ER) chaperone, can mediate calcium signals and vascular function within the endothelial cells (EC) of small resistance arteries. We found Calr protein expression significantly decreases with age in mesenteric arteries and examined the functional role of EC Calr in vasodilation and calcium mobilization in the con
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