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Additionally, the top-ranked compounds with much better docking rating were examined by in vitro MAO inhibitory assay. Compound umbelliferone ended up being observed as the most active hMAO-A inhibitor (IC50= 10.98±0.006 µM) and selectivity list of 0.607. In case there is hMAO-B activity lead compound rhamnetin shows the worth of 10.32±0.044 µM (SI worth of 3.096) as compared with pargyline (guide element) with IC50 worth of 20.04±0.095 µM. CONCLUSIONS These natural potentia