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© 2020 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim.The presence of regional metastasis is a predictor of worse survival in thick melanoma1 and is currently an indication for adjuvant therapy. Few studies have analyzed the prognostic role of clinical and pathologic variables in thick melanoma without metastatic lymph node involvement2-4 . The aim of this study was to identify them. This article is protected by copyright. All rights reserved.The most common denominator of many of the neurodegenerative diseases is the badly folded protei
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