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Non Stimulant ADHD Medication Stimulants increase dopamine and norepinephrine levels, which are neurotransmitters that assist in enhancing alertness, thinking, effort, and motivation. They also help improve concentration and focus. Non-stimulant ADHD medication is prescribed when stimulants don't work, cause serious adverse effects or when a person cannot take them due to medical reasons. Examples of this include clonidine (Kapvay) and guanfacine (Intuniv). Stimulants Stimulants are a kind of non-stimulant ADHD medication that works by changing how