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In addition to chance alone, input symptoms' variances and the regression coefficients or p values regarding mortality prediction are associated with the identification of significant syndromes.The common clinical symptoms of Friedreich's ataxia (FRDA) include ataxia, muscle weakness, type 2 diabetes and heart failure, which are caused by impaired mitochondrial function due to the loss of frataxin (FXN) expression. Endurance exercise is the most powerful intervention for promoting mitochondrial function; however, its impact on FRDA has no