https://tak1signal.com/index.p....hp/introducing-the-a
Tracing of the complex crosstalking system might trigger effective anti-ageing or neurodegenerative disease-modifying methods. In this review we present evidence on the crosstalk of proteostatic components with mitochondria and discuss how incorporating this knowledge in the future scientific studies might help us develop more efficacious treatments against aging and neurodegeneration.Allostatic load represents the 'wear and tear' of persistent stre