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Finding the Best ADHD Medication For Adults Medicines are the mainstay of a lot of adult ADHD treatment plans. But finding the right drug and dosage can be difficult. Stimulants: These medicines are used to treat hyperactivity and inattention. They work by increasing the levels of brain chemicals that transmit messages between nerve cells. They are usually taken multiple times per day and begin to work within less than an hour. Stimulants Most doctors begin with stimulants to treat ADHD. They work by boosting activity in specific areas of the