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First Line Treatment For ADHD in Adults Some people with ADHD are able to use medication to manage their symptoms. Stimulants such as methylphenidate or amphetamine help by enhancing brain activity in the areas that regulate attention and behavior. Other medications, like the nonstimulant atomoxetine as well as some antidepressants, function differently, but are equally efficient. People taking medication should see their GP regularly to monitor the effects on the body and adjust dos