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Among women with only submucous fibroids, the rate of surgical reintervention through 1year of follow up was 3.7% in FAST-EU and 0.0% in SONATA. With the Sonata system, TFA is an effective single-stage treatment option for non-pedunculated submucous myomata, and larger or deeper uterine fibroids (including fibroid clusters) for which hysteroscopic treatment is not suitable. ClinicalTrials.gov FAST-EU, NCT01226290; SONATA, NCT02228174. With the Sonata system, TFA is an effective single-stage treatment option for non-pedunculated submucou