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However, thinning of the syncytiocapillary membrane increases the risk of rupture and direct contact of the internal media of the mother and the fetus. Conclusions Sedentary lifestyle of a pregnant woman leads to structural and functional changes in the placenta, which can be a serious prerequisite for the development ofpathological abnormalities in the function of the "mother-placenta-fetus" system. To a certain extent, these changes are leveled due to compensatory processes in the placenta, the margin of efficacy of which needs further