https://www.selleckchem.com/pr....oducts/fatostatin.ht
Purpose We conducted a feasibility 2×2 factorial trial comparing N-methyl-D-aspartate (NMDA) antagonists (intravenous ketamine and oral memantine) versus placebo and intravenous steroids versus placebo, in patients having elective video-assisted thoracic surgery lobectomies, at St. Joseph's Hamilton, Canada, and Cleveland Clinic, Cleveland, USA. Our feasibility objectives were 1) recruitment rate/week; 2) recruitment of ≥90% of eligible patients; and 3) 90% follow-up. Secondary objectives were incidence and intensity of persisten