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Significantly more than 99percent of 10 mg·L-1 OTC could be eliminated within 48 h, additionally the anti-bacterial activity associated with MFC effluent on Escherichia coli DH5α was conclusively eliminated. High-throughput sequencing analysis uncovered that the variety and richness associated with microbial community reduced significantly after lasting OTC enrichment. Acinetobacter, Petrimonas, Spirochaetaceae and Delftia were enriched and played a dominant role in C-MFC stability and power generation. The marketing by Cupriavid