https://www.selleckchem.com/pr....oducts/pf-06882961.h
Interestingly, loss of Rgs7 in the striatum made mice resilient to stress-induced but not drug-induced reinstatement of cocaine CPP. Analysis of striatal proteome revealed that loss of Rgs7 selectively affected expression of several networks, most prominently including proteins involved in translation and vesicular exocytosis. Together, these findings begin to demonstrate the specific contribution of Rgs7 acting in the striatum toward depression as it relates to stress-induced reinstatement of drug use. While football injury and ill