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Experimental data from our group declare that kava, commonly consumed in the Southern Pacific Islands as a beverage to advertise leisure, may lower lung cancer tumors risk by improving NNK cleansing and decreasing NNK-derived DNA harm. Building upon these observations, we carried out a pilot clinical test to evaluate the consequences of a 7-day course of kava on NNK metabolism in active cigarette smokers. The principal objective was to compare urinary complete 4-(methylnitrosamino)-
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