https://www.selleckchem.com/pr....oducts/fumarate-hydr
Systemic sclerosis (scleroderma, SSc) is a chronic multisystem autoimmune disease characterised by fibrosis of the skin and internal organs and vasculopathy. One of the major contributors to mortality in patients with SSc is pulmonary arterial hypertension (PAH). International recommendations advise annual screening for the early detection of PAH in asymptomatic patients with SSc. To evaluate by systematic review current measures employed for screening for PAH. To summarise by meta-analysis the current evidence for long-