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We estimated that 33.82% (95%CI 14.97% to 47.84%) of total cancer hospitalizations could be attributed to PM exposure in Brazil during the study time. For every 100,000 population, 1,190 (95%CI 527 to 1,836) cancer hospitalizations, 8,191 (95%CI 3,627 to 11,587) inpatient days and US$788,775 (95%CI $349,272 to $1,115,825) cost were attributable to PM exposure. Long-term exposure to ambient PM was positively associated with hospitalization for many cancer types in Brazil. Inpatient days and cost would be saved if the annual PM exposure wa