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CD experiments showed architectural changes after addition of ZnPc 4, consistent with numerous binding modes and conformations shown by NMR and gel electrophoresis. CD melting confirmed that ZnPc 2 and ZnPc 4, both containing eight good fees, have the ability to support the AT11 G4 structure (ΔTm 30 °C and 18.5 °C, respectively). Molecular docking scientific studies of ZnPc 3 and ZnPc 4 advised a preferential binding towards the 3'- and 5'-end, correspondingly, of this AT11 G4.
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