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ADHD Medication UK For Adults The first prescription medication is typically a stimulant like methylphenidate. It increases activity in parts of the brain that control attention and behavior. Adults suffering from ADHD are more likely to benefit from long-acting formulations. They are gradually absorbed into the bloodstream and help avoid the 'crash' that can occur when short-acting medication wears off. Stimulants Stimulants are the most frequently prescribed medication for ADHD a