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10-2.0, but not in men (OR 1.47; 95% CI 0.94-2.3. In addition, a significant positive association was seen between caffeine intake and odds of IBS among subjects with BMI ≥ 25 kg/m2 (OR for those in the highest tertile vs. lowest tertile 1.72; 95% CI 1.20-2.48). There was a significant association between caffeine intake and IBS severity among subjects with BMI ≥ 25 kg/m2 (OR 1.04; 95% CI 1.01-2.62). In conclusion, coffee and caffeine consumption was associated with increased odds of IBS in the whole study population. The associati