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ADHD Medications and Treatments The primary drugs used to treat ADHD are stimulants. They boost neurotransmitters, which help control impulses and improve concentration. Adderall and dextroamphetamine are just two examples, as well as methylphenidate and lisdexamfetamine. Ritalin which are also known by their brand names. If stimulants don't work or cause too many adverse side effects, doctors may prescribe antidepressants, such as Wellbutrin. These medications target norepinep