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Background Scarce evidence exists on the diagnostic benefit of enteric contrast for abdominopelvic CT performed in the setting of penetrating trauma. Objectives The purpose of this systematic review and meta-analysis is to compare the diagnostic accuracy of CT using enteric contrast, with that of CT not using enteric contrast, in penetrating traumatic abdominopelvic injury in adults. Evidence Acquisition A protocol was registered a priori (PROSPERO CRD42019139613). MEDLINE and EMBASE were searched until June 25, 2019. Studies were includ