https://www.selleckchem.com/pr....oducts/paeoniflorin.
In this review, we discuss the structural features of the Lsm family proteins from different life domains and their structure-function relationships.The review focuses on bacterial metallo-β-lactamases (MβLs) responsible for the inactivation of β-lactams and associated antibiotic resistance. The diversity of the active site structure in the members of different MβL subclasses explains different mechanisms of antibiotic hydrolysis and should be taken into account when searching for potential MβL inhibitors. The review describes the
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