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iers and confirmed some of the previously mapped modifiers. Key genes involved mainly in metabolic and immunological processes were identified. Future steps in this analysis will be to identify regulatory elements - and possible epistatic effects - located in the mapped QTL. The presence of the human leukocyte antigen HLA-B*5701 is associated with the development of a hypersensitivity reaction to abacavir (ABC). Limited data exist on HLA-B*5701 prevalence in individuals with HIV-1 in Africa. This study aimed to estimate HLA-B*5701 prevalenc