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Right ventricle (RV) free wall and left ventricle global longitudinal strain decreased by 5.5% and 1.8%, respectively (P .001). Changes in NGAL correlated well with changes in serum creatinine (R = 0.79, P .01) and GFR (R = -0.73, P .05). Faster 21 km completion times, and a larger reduction in post-exercise RV strain, were associated with higher NGAL levels (R = -0.75, P = .01) and (R = 0.66, P .05), respectively. A 21 km run in recreational runners is associated with transient ventricular stunning and reversible c