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First Line Treatment For ADHD in Adults Some people suffering from ADHD are able to use medication to manage their symptoms. Stimulants such as methylphenidate or amphetamine help by enhancing brain activity in the areas that regulate behavior and attention. Other medications, like the nonstimulant atomoxetine as well as some antidepressants, function differently, but are equally effective. People taking medication should see their GP regularly to monitor the body's