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How Does For ADHD Work? Many kids and adults discover that ADHD medication helps improve their ability to concentrate and control impulses. It also helps them get organized. Your doctor will decide the best medication for your child after a consultation with you. Stimulants are the first-line treatment for ADHD. They increase the levels of two brain chemicals, norepinephrine and dopamine. Stimulants Stimulant medications for ADHD work by increasing the levels of certain brain chemicals (called neurotransmitters). This can help reduce symptoms, improves attention