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OBJECTIVE CircRNAs serve an essential role in regulating the development and progression of various tumors. The aim of this study was to examine the role and mechanism of circ_0009910 in hepatocellular carcinoma (HCC). MATERIALS AND METHODS RT-qPCR was used to detect the expression of circ_0009910 and miR-335-5p in tissues and cell lines of HCC. The proliferation, migration, and invasion of HCC cells were examined using 5-ethynyl-2-deoxyuridine (EdU), colony formation, and Transwell assay, respectively. Dual-luciferase reporter gene ass