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027), especially patients with stage I CRC (disease-free survival, = 0.015; overall survival, = 0.017). The Cox proportional hazards model identified FPR as an independent poor prognostic factor of disease-free survival (hazard ratio (HR) = 1.459, 95% confidence interval (CI) = 1.074-1.954, = 0.011) and overall survival (HR = 1.405, 95% CI = 1.034-1.909, = 0.03. The prognostic nomograms had good accuracy and were superior to the traditional TNM stage. FPR is a potential indicator for predicting short- and long-term prognosis of stage