https://www.selleckchem.com/pr....oducts/ly3522348.htm
OBJECTIVES Systemic sclerosis is a heterogeneous, multisystem disease. It can occur at any age, but most patients develop the disease between the age of 40 to 50 years. There is controversial evidence on whether/how the age at disease onset affects their clinical phenotype. We here investigate the relationship between age at disease onset and symptoms in a large cohort of SSc patients (lcSSc, dcSSc and SSc-overlap syndromes). METHODS Clinical data of the registry of the German Network for Systemic Scleroderma including 3281 patients w