https://www.selleckchem.com/pr....oducts/dubs-in-1.htm
We also discuss the disease relevance of each of these steps of telomerase biogenesis.Polyploidy (or whole-genome duplication) is the condition of having more than two basic sets of chromosomes. Polyploidization is well tolerated in many species and can lead to specific biological functions. In mammals, programmed polyploidization takes place during development in certain tissues, such as the heart and placenta, and is considered a feature of differentiation. However, unscheduled polyploidization can cause genomic instability and has
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