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While not all of the underlying systems of ANXA8 upregulation are elucidated, the interdependence of RA-RARA and ANXA8 appears to play a relevant role in some normal and tumorigenic settings.Anti-fibrotic therapies are of increasing interest to fight cardiac remodeling and heart failure development. Recently, anti-fibrotic circular RNAs (circRNAs) have now been identified in personal and rodent cardiac structure. In vivo (rodent) experiments proved cardiac anti-fi
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