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Objectives To explore the association of family-related adversities with physical fighting, and whether this association is mediated by hopelessness. Methods The sample consisted of 3712 Slovak adolescents (mean age 13.9, 50.7% girls). Participants answered questions regarding experienced family-related adversities, involvement in physical fighting in the last 12 months and the Hopelessness Questionnaire. First, the association of family adversities in general with fighting and of each of family-related adversity separately was assessed