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Treatment of Add in Adults Treatment for adults with add typically involves a combination of medication, life-skills training and psychotherapy. of patients respond to stimulant medications like methylphenidate, (Ritalin) and amphetamines, such as the lisdexamphetamine (Adderall XR) or extended-release mixed amphetamine salts. Stimulants can increase blood pressure and heartbeat. Non-stimulants like atomoxetine and bupropion can al