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Objectives We compared the quality of life (QoL) in children with precocious puberty (PP) and healthy children aged 8-12 years. Methods This descriptive and comparative study was conducted with 105 children with a diagnosis of PP and another 105 healthy children. We collected data using a Descriptive Information Form and the Pediatric Quality of Life Inventory (PedsQL). Results The mean overall PedsQL score (OS) was 78.71 ± 10.84 for children with PP and 82.43 ± 9.81 for healthy children (p less then .05). The mean PedsQL Proxy-Report OS