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According to the Youden index, the cut-off criteria was set to be Y 0.49, when its sensitivity and specificity were 82.4% and 84.6%, respectively. ConclusionAggravated nasal symptoms and decreased nasal ventilation could be seen after CDA provocation in the IR population. The CDA provocation provides a possible method for assisting the diagnosis of IR, and we'll expand the sample size in future research to verify its clinical application value.Cerebrospinal fluid (CSF) rhinorrhea is the result of an abnormal communication between sino