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Acute-on-chronic liver failure (ACLF) is divided into three types according to the underlying liver disease non-cirrhosis (type A), compensated cirrhosis (type and decompensated cirrhosis (type C). However, whether the underlying chronic liver diseases impact the ACLF prognosis is not clear. The present study aimed to compare the characteristics and outcomes of type A and type B hepatitis B virus (HBV)-ACLF patients. According to the European Association for the Study of Liver-Chronic Liver Failure (EASL-CLIF) diagnostic criteria, 86