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ADHD Treatment For Adults stimulants such as amphetamine and methylphenidate help boost levels of certain brain chemicals. Nonstimulants, such as atomoxetine and antidepressants, work slower than stimulants but they can be beneficial too. The comorbidity of conditions can affect the response to ADHD medications. Physicians should address the most severe symptoms of any comorbid disorder first, then monitor whether the ADHD symptoms improve. Medication Adults suffe