https://www.selleckchem.com/pr....oducts/buloxibutid.h
As the cGMP pathway plays important roles in melanocyte (patho)physiology, we present an overview on the differential effects of altered gravity (hypergravity/simulated microgravity) on the cGMP signaling pathway in melanocytes and melanoma cells with different metastatic potential. We believe that future experiments in real microgravity may benefit from considering cGMP signaling as a possible factor for melanocyte transformation and in medication.Arginase II reciprocally regulates endothelial nitric oxide synthase (eNOS) through a