https://www.selleckchem.com/pr....oducts/dt-061-smap.h
Intra-abdominal hypertension (IAH) in acute pancreatitis (AP) is associated with deterioration in organ function. This trial aimed to assess the efficacy of neostigmine for IAH in patients with AP. In this single-center, randomized trial, consenting patients with IAH within 2weeks of AP onset received conventional treatment for 24h. Patients with sustained intra-abdominal pressure (IAP) ≥ 12mmHg were randomized to receive intramuscular neostigmine (1mg every 12h increased to every 8h or every 6h, depending on response) or continue c
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